Frustratometer

There is a new version for this service, check it here. The Frustratometer is an Energy Landscape Theory inspired algorithm that aims at quantifying the degree of local frustration manifested in protein molecules. Frustration is a useful concept for gaining insight to the proteins biological behavior by analyzing how the energy is distributed in protein structures and how mutations or conformational changes shift the energy distributions. Sites of high local frustration often indicate biologically important regions such as binding or allosteric sites. Minimally frustrated linkages constitute a stable folding core of the molecule.

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This server and its associated data and services are for research purpose only, not for clinical or commercial use. It is a non-profit service to the scientific community. The responsibility of Universidad de Buenos Aires is limited to applying best efforts in providing and publishing good programs and data. Universidad de Buenos Aires has no responsibility for the use of results, data or information which have been provided through this server.

How to cite this application

NGOME: prediction of non-enzymatic protein deamidation from sequence-derived secondary structure$ J. Ramiro Lorenzo, Leonardo G. Alonso and Ignacio E. Sánchez
EMBnet node Argentina, www.embnet.qb.fcen.uba.ar


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